Vatican City is the smallest independent state in the world, both in terms of area and population, and it serves primarily as a religious and administrative center for the Roman Catholic Church. The territory is home to St. Peter’s Basilica, the Apostolic Palace (the residence of the Pope), the Vatican Museums, and other religious buildings, rather than commercial hotels or spas.

However, if you’re looking for luxury spa hotels near Vatican City, there are excellent options just beyond its walls, particularly in the Prati and Borgo neighborhoods of Rome, including:

Nearby Spa Hotels in Rome (walking distance from Vatican City):

• Gran Meliá Rome 
  Features a serene spa (Clarins My Blend Spa), garden views, and proximity to the Vatican.
• Rome Cavalieri, A Waldorf Astoria Hotel
  Located a bit farther out, but offers a luxurious spa experience with panoramic city views.
• Hotel Indigo Rome – St. George
  A boutique hotel with a wellness center and Turkish bath, just a short walk from the Vatican.